Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Z2CN
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Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Z2CN
Price: ￥498.0/5ml
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Aminopropionitrile
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: β-aminopropionitrile
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Purity: 99.0%
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151-18-8

151-18-8 structure

151-18-8 structure

Name: Z2CN
Chemical Name: β-aminopropionitrile
CAS Number: 151-18-8
Molecular Formula: C₃H₆N₂
Molecular Weight: 70.093
Catalog: Chemical reagent Organic reagent Cyanide/nitrile
Create Date: 2018-04-03 08:00:00
Modify Date: 2025-08-22 13:13:41
β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes[1][2].

Name	β-aminopropionitrile
Synonyms	3-Amino-1-propanethiolHCl Propanenitrile, 3-amino- chlorhydrate de mercapto-3 propylamine 3-amino-propionitrile 3-mercapto-1-propylamino hydrochloride 3-Aminopropionitrile 3-Mercaptopropylamine hydrochloride EINECS 205-786-0 MFCD00014820 Z2CN N-(2-Cyanoethyl)amine beta-aminopropionitrile 2-Cyanoethylamine 3-cyanoethylamine 3-aminopropanonitrile 1-Propanethiol,3-aMino-,hydrochloride 3-Aminopropionitrile Fumarate 3-thiopropylamine hydrochloride 3-Aminopropanenitrile aminopropylthiol hydrochloride β-Aminopropionitrile homocysteamine hydrochloride 3-aminopropanethiol hydrochloride aminoethylcyanide

Description	β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Target	Human Endogenous Metabolite
In Vitro	β-Aminopropionitrile blocks the hypoxia-induced EMT morphological and marker protein changes, and inhibited invasion and migration capacities of cervical carcinoma cells in vitro[2].
References	[1]. Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51. [2]. Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8.

Density	0.9±0.1 g/cm3
Boiling Point	186.3±13.0 °C at 760 mmHg
Molecular Formula	C₃H₆N₂
Molecular Weight	70.093
Flash Point	66.5±19.8 °C
Exact Mass	70.053101
PSA	49.81000
LogP	-1.02
Vapour Pressure	0.7±0.4 mmHg at 25°C
Index of Refraction	1.430

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UG0350000

CHEMICAL NAME :: Propionitrile, 3-amino-

CAS REGISTRY NUMBER :: 151-18-8

BEILSTEIN REFERENCE NO. :: 1698848

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C3-H6-N2

MOLECULAR WEIGHT :: 70.11

WISWESSER LINE NOTATION :: Z2CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12800 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1152 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg/11D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 5 gm/kg

SEX/DURATION :: female 14-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1250 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1250 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - mouse Embryo

DOSE/DURATION :: 1250 mg/kg

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 47,305,1981

Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S36/37
RIDADR	3276
RTECS	UG0350000
Packaging Group	III
Hazard Class	8
HS Code	2926909090

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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