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89250-26-0

89250-26-0 structure
89250-26-0 structure
  • Name: 2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole
  • Chemical Name: 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole
  • CAS Number: 89250-26-0
  • Molecular Formula: C10H7ClN2O2S
  • Molecular Weight: 254.69
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-02-03 08:00:00
  • Modify Date: 2025-08-24 10:16:38
  • 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by repression of M2 polarization of Tumor-associated macrophages (TAMs). 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole can be isolated from Astragalus propinquus Schischk[1].
Name 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole
Synonyms 2-(chloromethyl)-4-(4-nitrophenyl)-1,3-thiazole
Description 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by repression of M2 polarization of Tumor-associated macrophages (TAMs). 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole can be isolated from Astragalus propinquus Schischk[1].
Related Catalog
References

[1]. Li C, et al. Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages. Pharm Biol. 2021 Dec;59(1):1533-1539.  

Density 1.4±0.1 g/cm3
Boiling Point 406.2±30.0 °C at 760 mmHg
Melting Point 154.5ºC
Molecular Formula C10H7ClN2O2S
Molecular Weight 254.69
Flash Point 199.5±24.6 °C
Exact Mass 253.991669
PSA 86.95000
LogP 2.71
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.638
Hazard Codes Xi
Risk Phrases 34
Safety Phrases 22-26-36/37/39-45
HS Code 2932999099
4414-98-6 structure

4414-98-6

~%

89250-26-0 structure

89250-26-0

Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060
4414-97-5 structure

4414-97-5

~%

89250-26-0 structure

89250-26-0

Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060
99-81-0 structure

99-81-0

~%

89250-26-0 structure

89250-26-0

Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060
65385-00-4 structure

65385-00-4

~%

89250-26-0 structure

89250-26-0

Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060
HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
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title: CAS No. 89250-26-0 | Chemsrc address: https://www.chemsrc.com/en/baike/829753.html

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