2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole structure
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Common Name | 2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole | ||
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| CAS Number | 89250-26-0 | Molecular Weight | 254.69 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 406.2±30.0 °C at 760 mmHg | |
| Molecular Formula | C10H7ClN2O2S | Melting Point | 154.5ºC | |
| MSDS | N/A | Flash Point | 199.5±24.6 °C | |
Use of 2-(Chloromethyl)-4-(4-Nitrophenyl)-1,3-Thiazole2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by repression of M2 polarization of Tumor-associated macrophages (TAMs). 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole can be isolated from Astragalus propinquus Schischk[1]. |
| Name | 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole |
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| Synonym | More Synonyms |
| Description | 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by repression of M2 polarization of Tumor-associated macrophages (TAMs). 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole can be isolated from Astragalus propinquus Schischk[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 406.2±30.0 °C at 760 mmHg |
| Melting Point | 154.5ºC |
| Molecular Formula | C10H7ClN2O2S |
| Molecular Weight | 254.69 |
| Flash Point | 199.5±24.6 °C |
| Exact Mass | 253.991669 |
| PSA | 86.95000 |
| LogP | 2.71 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.638 |
| InChIKey | LEBRGKZHLICZCZ-UHFFFAOYSA-N |
| SMILES | O=[N+]([O-])c1ccc(-c2csc(CCl)n2)cc1 |
| Hazard Codes | Xi |
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| Risk Phrases | 34 |
| Safety Phrases | 22-26-36/37/39-45 |
| HS Code | 2932999099 |
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~%
2-(Chloromethyl... CAS#:89250-26-0 |
| Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060 |
|
~%
2-(Chloromethyl... CAS#:89250-26-0 |
| Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060 |
|
~%
2-(Chloromethyl... CAS#:89250-26-0 |
| Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060 |
|
~%
2-(Chloromethyl... CAS#:89250-26-0 |
| Literature: Zhurnal Obshchei Khimii, , vol. 24, p. 1059,1062; engl. Ausg. S. 1057, 1060 |
| HS Code | 2934100090 |
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| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
| 2-(chloromethyl)-4-(4-nitrophenyl)-1,3-thiazole |