86770-67-4

86770-67-4 structure

Name: Azido-PEG4-alcohol
Chemical Name: 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol
CAS Number: 86770-67-4
Molecular Formula: C₈H₁₇N₃O₄
Molecular Weight: 219.23800
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-01-09 19:42:37
Modify Date: 2025-08-24 18:30:31
Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol
Synonyms	1-AZIDO-3,6,9-TRIOXAUNDECANE-11-OL Azido-PEG4-alcohol 1-azido-3,6,9-trioxaundecan-11-ol 1-azido-11-hydroxy-3,6,9-trioxaundecane

Description	Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.