106984-09-2

106984-09-2 structure

Name: N-Boc-PEG4-alcohol
Chemical Name: 1-Boc-amino-3,6,9-trioxaundecanyl-11-ol
CAS Number: 106984-09-2
Molecular Formula: C₁₃H₂₇NO₆
Molecular Weight: 293.35700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-07-18 21:48:42
Modify Date: 2024-01-06 14:42:34
PROTAC Linker 12 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 12 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	1-Boc-amino-3,6,9-trioxaundecanyl-11-ol
Synonyms	tert-butyl N-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]carbamate N-Boc-PEG4-alcohol

Description	PROTAC Linker 12 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 12 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Hazard Codes	Xn
HS Code	2924199090

24424-99-5

86770-74-3

~87%

106984-09-2

24424-99-5

86770-67-4

~52%

106984-09-2

34619-03-9

86770-74-3

~84%

106984-09-2

112-60-7

106984-09-2

86770-67-4

106984-09-2

65883-12-7

106984-09-2

77544-60-6

106984-09-2

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%