Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NH2-PEG8-OH
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Amino-PEG8-alcohol
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Amino-PEG8-alcohol
Price: $500.0/100mg $850.0/250mg $1700.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-Aminooctaethylene Glycol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

352439-37-3

352439-37-3 structure

352439-37-3 structure

Name: NH2-PEG8-OH
Chemical Name: 1-Aminooctaethylene Glycol
CAS Number: 352439-37-3
Molecular Formula: C₁₆H₃₅NO₈
Molecular Weight: 369.45100
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-04-19 17:59:26
Modify Date: 2025-08-25 12:57:49
NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-Aminooctaethylene Glycol
Synonyms	1-amino-2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol

Description	NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₆H₃₅NO₈
Molecular Weight	369.45100
Exact Mass	369.23600
PSA	110.86000

Hazard Codes	Xi

352439-36-2 structure

352439-36-2

~90%

352439-37-3 structure

352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

112-60-7 structure

112-60-7

~%

352439-37-3 structure

352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

86770-67-4 structure

86770-67-4

~%

352439-37-3 structure

352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

134179-43-4 structure

134179-43-4

~%

352439-37-3 structure

352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

65883-12-7 structure

65883-12-7

~%

352439-37-3 structure

352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

125274-16-0 structure

125274-16-0

~%

352439-37-3 structure

352439-37-3

Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

Precursor 6
352439-36-2 112-60-7 86770-67-4 134179-43-4
65883-12-7 125274-16-0
DownStream 0

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