Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sedanolide
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Sedanolide
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sedanolide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

6415-59-4

6415-59-4 structure

6415-59-4 structure

Name: Sedanolide
Chemical Name: 3-butyl-3a,4,5,6-tetrahydro-3H-2-benzofuran-1-one
CAS Number: 6415-59-4
Molecular Formula: C₁₂H₁₈O₂
Molecular Weight: 194.27000
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2018-04-10 08:00:00
Modify Date: 2025-08-20 12:50:12
Sedanolide, a natural compound occurring in edible umbelliferous plants, possesses anti-inflammatory and antioxidant activities[1][2].

Name	3-butyl-3a,4,5,6-tetrahydro-3H-2-benzofuran-1-one
Synonyms	Neocnidilide 3-butyl-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-one Sedanolide MFCD00171327

Description	Sedanolide, a natural compound occurring in edible umbelliferous plants, possesses anti-inflammatory and antioxidant activities[1][2].
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology
In Vitro	Sedanolide induces autophagy through the PI3K, p53 and NF-κB signaling pathways in human liver cancer cells[2].
In Vivo	Sedanolide increases the activity of glutathione-S-transferase (GST) in the liver, small intestinal mucosa, and forestomach of A/J mice[1].
References	[1]. J A Woods， et al. Sedanolide, a Natural Phthalide From Celery Seed Oil: Effect on Hydrogen Peroxide and Tert-Butyl Hydroperoxide-Induced Toxicity in HepG2 and CaCo-2 Human Cell Lines. In Vitr Mol Toxicol. Fall 2001;14(3):233-40. [2]. Shu-Ling Hsieh, et al. Sedanolide Induces Autophagy Through the PI3K, p53 and NF-κB Signaling Pathways in Human Liver Cancer Cells. Int J Oncol. 2015 Dec;47(6):2240-6.

Density	1.03
Boiling Point	342.0±11.0 °C(Predicted)
Melting Point	120 °C
Molecular Formula	C₁₂H₁₈O₂
Molecular Weight	194.27000
Exact Mass	194.13100
PSA	26.30000
LogP	2.82850
Index of Refraction	1.742

Hazard Codes	Xi
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36

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