4567-33-3

4567-33-3 structure

Name: Neocnidilide
Chemical Name: (3S,3aR)-3-butyl-3a,4,5,6-tetrahydro-3H-2-benzofuran-1-one
CAS Number: 4567-33-3
Molecular Formula: C₁₂H₁₈O₂
Molecular Weight: 194.27000
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2017-05-09 13:22:18
Modify Date: 2025-08-25 15:18:55
Neocnidilide is an alkylphthalide, which has the activity of inhibiting the growth of mycotoxin-producing fungi. Neocnidilide also has larvicidal activity against D. melanogaster with a LC50 value of 9.9 μmol/mL[1][2].

Name	(3S,3aR)-3-butyl-3a,4,5,6-tetrahydro-3H-2-benzofuran-1-one
Synonyms	trans-3-Butyl-4,5,6,7-tetrahydrophthalid (3S,3aR)-(-)-Sedanolide Neocnidilide 1(3H)-Isobenzofuranone,3-butyl-3a,4,5,6-tetrahydro-,cis-(-) (3aR)-3c-Butyl-(3ar)-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-on (3aR)-3c-butyl-(3ar)-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-one

Description	Neocnidilide is an alkylphthalide, which has the activity of inhibiting the growth of mycotoxin-producing fungi. Neocnidilide also has larvicidal activity against D. melanogaster with a LC50 value of 9.9 μmol/mL[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Xiao-Zhen Jiao, et al. Study of stereoselective synthesis of (+/-)-neocnidilide. J Asian Nat Prod Res. 2003 Sep;5(3):165-9. [2]. Toshihiko Tsukamoto, et al. Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem. 2005 Jul 13;53(14):5549-53.