Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Alpha-Naphthylflavone
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+/-)-Nicotine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Pyridine,3-(1-methyl-2-pyrrolidinyl)-
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

22083-74-5

22083-74-5 structure

22083-74-5 structure

Name: (±)-nicotine
Chemical Name: nicotine
CAS Number: 22083-74-5
Molecular Formula: C₁₀H₁₄N₂
Molecular Weight: 162.232
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-07-12 20:38:52
Modify Date: 2025-08-20 13:31:15

Name	nicotine
Synonyms	vrzjvuppqwdfac-yhyxmxqvsa (R,S)-nicotine (RS)-nicotine 3-(1-Methyl-2-pyrrolidinyl)pyridine fdhr 3-(1-methyl-2-pyrrolidinyl)-Pyridine 1-Methyl-2-(3-pyridyl)pyrrolidine MFCD00065370 (+/-)-nicotine Pyridine, 3-(1-methyl-2-pyrrolidinyl)- Pyridine, 3-(1-methyl-2-pyrrolidinyl)- (9CI) (±)-3-(1-Methyl-2-pyrrolidinyl)pyridine DL-Nicotine (±)-nicotine 3-(1-Methylpyrrolidin-2-yl)pyridine Nicotine

Density	1.0±0.1 g/cm3
Boiling Point	244.4±28.0 °C at 760 mmHg
Melting Point	-79ºC
Molecular Formula	C₁₀H₁₄N₂
Molecular Weight	162.232
Flash Point	101.7±0.0 °C
Exact Mass	162.115692
PSA	16.13000
LogP	0.72
Appearance	liquid \| yellow
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.539
Storage condition	Refrigerator
Water Solubility	ethanol: 50 mg/mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QS5257500

CHEMICAL NAME :: Nicotine, (+-)-

CAS REGISTRY NUMBER :: 22083-74-5

BEILSTEIN REFERENCE NO. :: 0082111

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H14-N2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 31250 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 50,93,1934

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 50,93,1934

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 2 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 50,93,1934

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 50,93,1934

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H310-H411
Precautionary Statements	P273-P280-P301 + P310-P302 + P350-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T+: Very toxic;N: Dangerous for the environment;
Risk Phrases	25-27-51/53
Safety Phrases	36/37-45-61
RIDADR	UN 1654 6.1/PG 2
WGK Germany	3
RTECS	QS5257500

Precursor 8
50-00-0 5746-86-1 64-18-6 25162-00-9
125630-28-6 74-89-5 76014-80-7 180407-32-3
DownStream 9
74-89-5 487-19-4 120-94-5 54-11-5
25162-00-9 532-12-7 15569-85-4 89100-79-8
5746-86-1

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