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621-23-8

621-23-8 structure
621-23-8 structure

Name 1,3,5-trimethoxybenzene
Synonyms Benzene,1,3,5-trimethoxy
1,3,5-trimethoxy-benzene
Benzene, 1,3,5-trimethoxy-
1,3,5-Trimethoxybenzene
tri-O-methylphloroglucinol
phloroglucinol trimethyl ether
2,4,6-Trimethoxybenzene
1,3,5-Trimethyoxybenzene
1,3,5-trimethoxy-benzen
sym-Trimethoxybenzene
2,4,6-trimethoxyiodobenzene
1,3,5-Trimethoxybenz
1,3,5-trimethoxyarene
MFCD00008385
5-TriMethoxybenzene
TRISMETHOXYBENZENE
3,5-DIMETHOXYANISOLE
EINECS 210-673-4
Description 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor. 1,3,5-Trimethoxybenzene is an effective sedative[1].
Related Catalog
References

[1]. Wu S, et al. The key role of phloroglucinol O-methyltransferase in the biosynthesis of Rosa chinensis volatile 1,3,5-trimethoxybenzene. Plant Physiol. 2004 May;135(1):95-102.

Density 1.0±0.1 g/cm3
Boiling Point 257.0±20.0 °C at 760 mmHg
Melting Point 50-53 °C(lit.)
Molecular Formula C9H12O3
Molecular Weight 168.190
Flash Point 85.6±0.0 °C
Exact Mass 168.078644
PSA 27.69000
LogP 1.61
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.485
Water Solubility insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DC2810000
CHEMICAL NAME :
Benzene, 1,3,5-trimethoxy-
CAS REGISTRY NUMBER :
621-23-8
BEILSTEIN REFERENCE NO. :
1307993
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H12-O3
MOLECULAR WEIGHT :
168.21
WISWESSER LINE NOTATION :
1OR CO1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,187,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
580 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,187,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,187,1969
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22
Safety Phrases S24/25
RIDADR 1325
WGK Germany 3
RTECS DC2810000
Packaging Group III
Hazard Class 4.1
HS Code 29093090
HS Code 2909309090
Summary 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%