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  • Product Name: Flavokawain A
  • Price: ¥Inquiry/10mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng



3420-72-2

3420-72-2 structure
3420-72-2 structure
  • Name: Flavokawain A
  • Chemical Name: 2'-hydroxy-4,4',6'-trimethoxychalcone
  • CAS Number: 3420-72-2
  • Molecular Formula: C18H18O5
  • Molecular Weight: 314.332
  • Catalog: Natural product Chalcone
  • Create Date: 2018-12-29 18:50:50
  • Modify Date: 2024-01-02 17:58:04
  • Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].

Name 2'-hydroxy-4,4',6'-trimethoxychalcone
Synonyms FLAVOKAWIN A
1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one
Flavokavin A
MFCD00017174
2'-Hydroxy-4,4',6'-trimethoxy-trans-chalcone
2'-Hydroxy-4,4',6'-trimethoxy
flavokawain-A
2'-hydroxy-4',6'-dimethoxyphenyl-4-methoxystyrylketone
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-
2'-hydroxy-4,4',6'-trimethoxy-chalcone
Flavokawain A
Description Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].
Related Catalog
References

[1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.

Density 1.2±0.1 g/cm3
Boiling Point 529.9±50.0 °C at 760 mmHg
Melting Point 112-116 °C(lit.)
Molecular Formula C18H18O5
Molecular Weight 314.332
Flash Point 193.2±23.6 °C
Exact Mass 314.115417
PSA 64.99000
LogP 3.96
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.600
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2914509090
HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%