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69123-94-0

69123-94-0 structure
69123-94-0 structure
  • Name: 2'-Deoxy-2'-fluorouridine
  • Chemical Name: 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
  • CAS Number: 69123-94-0
  • Molecular Formula: C9H11FN2O5
  • Molecular Weight: 246.19
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-12-26 13:51:48
  • Modify Date: 2024-01-14 06:21:16
  • 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Name 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
Synonyms 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione
2'-Deoxy-2'-fluorouridine
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione
Uridine, 2'-deoxy-2'-fluoro-
2'-Fluoro-2'-deoxyuridine
1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil
Description 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.6±0.1 g/cm3
Molecular Formula C9H11FN2O5
Molecular Weight 246.19
Exact Mass 246.065201
PSA 104.55000
LogP -1.31
Index of Refraction 1.608
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9512000
CHEMICAL NAME :
Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
CAS REGISTRY NUMBER :
69123-94-0
LAST UPDATED :
198708
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C11-H15-F-N2-O5
MOLECULAR WEIGHT :
274.28
WISWESSER LINE NOTATION :
T6NVMVJ E2 A- BT5OTJ CF DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - rat Bone marrow
DOSE/DURATION :
3700 umol/L
REFERENCE :
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 26,333,1985
HS Code 2934999090
Precursor  0

DownStream  2

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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title: CAS No. 69123-94-0 | Chemsrc address: https://www.chemsrc.com/en/baike/524686.html

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