2'-Deoxy-2'-fluorouridine

Modify Date: 2025-08-23 16:25:14

2'-Deoxy-2'-fluorouridine structure	Common Name	2'-Deoxy-2'-fluorouridine
	CAS Number	69123-94-0	Molecular Weight	246.19
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₉H₁₁FN₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-Deoxy-2'-fluorouridine

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
Synonym	More Synonyms

Description	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.6±0.1 g/cm3
Molecular Formula	C₉H₁₁FN₂O₅
Molecular Weight	246.19
Exact Mass	246.065201
PSA	104.55000
LogP	-1.31
Index of Refraction	1.608
InChIKey	UIYWFOZZIZEEKJ-PXBUCIJWSA-N
SMILES	O=c1ccn(C2OC(CO)C(O)C2F)c(=O)[nH]1
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ9512000

CHEMICAL NAME :: Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-

CAS REGISTRY NUMBER :: 69123-94-0

LAST UPDATED :: 198708

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H15-F-N2-O5

MOLECULAR WEIGHT :: 274.28

WISWESSER LINE NOTATION :: T6NVMVJ E2 A- BT5OTJ CF DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rat Bone marrow

DOSE/DURATION :: 3700 umol/L

REFERENCE :: PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 26,333,1985

HS Code	2934999090

Precursor 0
DownStream 2
CAS#:66-22-8 Uracil CAS#:122757-52-2 1-[(2R,5S)-3-Fl...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione

2'-Deoxy-2'-fluorouridine

2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione

Uridine, 2'-deoxy-2'-fluoro-

2'-Fluoro-2'-deoxyuridine

1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2'-Deoxy-2'-fluorouridine
Price: Check
Purity: 99.16%
Delivery: 10 Day
Contact: Yang
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2'-Deoxy-2'-fluorouridine
Price: ￥1598.0/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(2-DEOXY-2-FLUORO-B-D-ARABINOFURANOSYL)URACIL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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2'-Deoxy-2'-fluorouridine

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