| Name | N-Succinimidyl 6-maleimidohexanoate |
|---|---|
| Synonyms |
1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
MFCD00043043 1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione 1H-pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]- (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate N-succinimidyl-6-maleimidocaproate 6-Maleimidohexanoic acid N-hydroxysuccinimide ester MCOSU EMCS |
| Description | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 480.6±47.0 °C at 760 mmHg |
| Melting Point | 70-73 °C(lit.) |
| Molecular Formula | C14H16N2O6 |
| Molecular Weight | 308.287 |
| Flash Point | 244.5±29.3 °C |
| Exact Mass | 308.100830 |
| PSA | 101.06000 |
| LogP | -0.81 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.577 |
| Storage condition | −20°C |
| Water Solubility | chloroform: 100mg/mL |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H351 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful;Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
|
~91%
55750-63-5 |
| Literature: MacBeath; Hilvert Journal of the American Chemical Society, 1994 , vol. 116, # 14 p. 6101 - 6106 |
|
~82%
55750-63-5 |
| Literature: Ikeda, Masato; Ochi, Rika; Kurita, Yu-Shi; Pochan, Darrin J.; Hamachi, Itaru Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13091 - 13096 |
|
~38%
55750-63-5 |
| Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798 |
|
~%
55750-63-5 |
| Literature: Organic and Biomolecular Chemistry, , vol. 7, # 17 p. 3400 - 3406 |
|
~%
55750-63-5 |
| Literature: Journal of Organic Chemistry, , vol. 76, # 21 p. 9169 - 9174 |
| Precursor 6 | |
|---|---|
| DownStream 1 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |