Abstract: We have developed an immunoassay for screening large libraries of potential catalysts of a bimolecular Diels-Alder reaction. The procedure involves the reaction of immobilized dienophile with diene in solution and subsequent detection of the product with a monoclonal antibody as in a regular enzyme-linked immunosorbant assay (ELISA). The assay exhibits the expected dependence on time and diene concentration. A catalytic ...
