6-Maleimidocapronic acid structure
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Common Name | 6-Maleimidocapronic acid | ||
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CAS Number | 55750-53-3 | Molecular Weight | 211.214 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 407.3±28.0 °C at 760 mmHg | |
Molecular Formula | C10H13NO4 | Melting Point | 86-91ºC | |
MSDS | Chinese USA | Flash Point | 200.1±24.0 °C | |
Symbol |
GHS05, GHS07 |
Signal Word | Danger |
Use of 6-Maleimidocapronic acid6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | 6-Maleimidocaproic Acid |
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Synonym | More Synonyms |
Description | 6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
Alkyl-Chain |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 407.3±28.0 °C at 760 mmHg |
Melting Point | 86-91ºC |
Molecular Formula | C10H13NO4 |
Molecular Weight | 211.214 |
Flash Point | 200.1±24.0 °C |
Exact Mass | 211.084457 |
PSA | 74.68000 |
LogP | 0.71 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.537 |
Storage condition | 2-8°C |
Symbol |
GHS05, GHS07 |
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Signal Word | Danger |
Hazard Statements | H315-H318-H335 |
Precautionary Statements | P261-P280-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2925190090 |
~71% 6-Maleimidocapr... CAS#:55750-53-3 |
Literature: Dalton Transactions, , # 24 p. 3886 - 3897 |
~74% 6-Maleimidocapr... CAS#:55750-53-3 |
Literature: Journal of Medicinal Chemistry, , vol. 56, # 24 p. 9955 - 9968 |
~30% 6-Maleimidocapr... CAS#:55750-53-3 |
Literature: EP665020 A3, ; |
~% 6-Maleimidocapr... CAS#:55750-53-3 |
Literature: US8241655 B2, ; |
~% 6-Maleimidocapr... CAS#:55750-53-3 |
Literature: Dalton Transactions, , # 24 p. 3886 - 3897 |
HS Code | 2925190090 |
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Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid |
MFCD00043140 |
1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo- |
6-(2,5-dioxopyrrol-1-yl)hexanoic acid |