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10127-02-3

10127-02-3 structure
10127-02-3 structure
  • Name: Basic Orange 14
  • Chemical Name: Basic Orange 14
  • CAS Number: 10127-02-3
  • Molecular Formula: C34H40Cl4N6Zn
  • Molecular Weight: 739.943
  • Catalog: Dyes and pigments dye Basic dye
  • Create Date: 2018-09-02 18:19:26
  • Modify Date: 2025-08-21 21:27:55
  • Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
Name Basic Orange 14
Synonyms N,N,N',N'-Tetramethyl-3,6-acridinediamine - dichlorozinc (2:1) dihydrochloride
Acridine Orange hemi(zinc chloride) salt
MFCD00081043
zinc,3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine,dichloride,hydrochloride
Acridine Orange
N,N,N',N'-Tetramethyl-3,6-acridinediamine - dichlorozinc hydrochloride (2:1:2)
Euchrysin GNY
EINECS 200-614-0
Description Acridine Orange (Euchrysine 3RX) zinc chloride salt is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange zinc chloride salt produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
Related Catalog
In Vitro Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)[4]. 1. 用 Acridine Orange zinc chloride salt 染色细胞 (1 μM; 20 分钟; 37 ℃)。 2. 用 PBS 洗涤细胞。 3. 通过共聚焦激光扫描显微镜 (FV3000，Olympus) 观察细胞。
In Vivo Acridine Orange (0.1 mg/kg，静脉注射，狗) zinc chloride salt 在 30 天内没有表现出临床毒性迹象，血液中也没有发现异常[1]。
References

[1]. McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8.  

[2]. Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56.  

[3]. Byvaltsev VA, et al. Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy. Front Oncol. 2019 Sep 24;9:925.  

[4]. Wang Q, et al. Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement. Cell Prolif. 2022 Jan;55(1):e13172.  

Boiling Point 468.6ºC at 760 mmHg
Melting Point 165 °C
Molecular Formula C34H40Cl4N6Zn
Molecular Weight 739.943
Flash Point 237.2ºC
Exact Mass 736.135986
PSA 38.74000
LogP 10.02050
Storage condition Store at RT.
Water Solubility soluble
Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H341
Precautionary Statements P281
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22;R68
Safety Phrases S45-S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AR7600000
Packaging Group I; II; III
Hazard Class 6.1
HS Code 32041300
HS Code 32041300
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