| Name | dl-laudanosine |
|---|---|
| Synonyms |
(R)-Laudanosine
LAUDANOSINE,DL-(SH) (+/-)-LAUDANOSIDE (+-)-laudanosine LAUDANOSINE,DL-(SH)(CALL) LAUDANOSINE,DL DL-LAUDANOSIDE |
| Description | DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity[1]. |
|---|---|
| Related Catalog | |
| In Vivo | DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses[1]. Animal Model: Male CFLP mice weighing 18-25 g, and male Wistar rats weighing 120-150 g [2]. Dosage: 10-20 mg/kg. Administration: IV. Result: Caused convulsions and hind limb extensions. |
| References |
| Melting Point | 115℃ |
|---|---|
| Molecular Formula | C21H27NO4 |
| Molecular Weight | 357.44300 |
| Exact Mass | 357.19400 |
| PSA | 40.16000 |
| LogP | 3.43060 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331 |
| Precautionary Statements | Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233 |
| Risk Phrases | 26/28-40 |
| Safety Phrases | 22-24/25 |
| RIDADR | UN 2810 |
| HS Code | 2933499090 |
| Precursor 0 | |
|---|---|
| DownStream 9 | |
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |