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3326-32-7

3326-32-7 structure
3326-32-7 structure
Name fluorescein 5-isothiocyanate
Synonyms 5-FITC
Isothiocyanatofluorescein
5-Isothionatofluorescein
Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-isothiocyanato-
FITC Fluorescein 5-isothiocyanate
EINECS 248-207-7
Fluorescein Isothiosyanate
fluorescein isothiocyanate isomer 1
fluorescein 6-isothiocyanate
FITC ISOMER
Fluorescein 5-Isothiocyanate (isomer I)
3',6'-Dihydroxy-5-isothiocyanato-3H-spiro[2-benzofurane-1,9'-xanthén]-3-one
5-FITC (isomer I)
5-Isothiocyanatofluorescein (isomer I)
FITC
5-Fluorescein Isothiocyanate
fluorescein 5-isothiocyanate
FITC,Fluorescein 5-isothiocyanate
FITC isomer I
Fluorescein isothiocyanate,isomer 1
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-isothiocyanatobenzoic acid
Fluorescein Isothiocyanate (isomer I)
Fluorescein isothiocyanate isomer I
Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato-
FITC-I
Fluorescein 5(6)-isothiocyanate
Fluorescein-5-isothiocyanate
MFCD00005063
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-5-isothiocyanato-
Fluorescein Isothiocyanate
3',6'-Dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
Description FITC is a derivative of fluorescein for the labeling of amines.
Related Catalog
In Vitro Annexin V-FITC/PI is employed to detect chondrocyte apoptosis[1]. The PEI-modified CDs are conjugated with fluorescein isothiocyanate (FITC) to fabricate CDs-FITC composites[2].
Cell Assay The frequency of chondrocyte apoptosis is measured by flow cytometry with Annexin V-fluorescein isothiocyanate (FITC) and propidium iodide. A total of 1×104 treated chondrocytes are collected from each group, washed in cold PBS and incubated with Annexin V-FITC and PI at room temperature for 15 min in the dark on ice. These samples are then analyzed using a fluorescence-activated cell sorter. Cell Quest software is used to analyze the percentage of apoptosis. All tests are repeated in triplicate.
References

[1]. Gao SG, et al. Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes. Exp Ther Med. 2016 Nov;12(5):3488-3494. Epub 2016 Oct 5.

[2]. Zhu X, et al. Ratiometric, visual, dual-signal fluorescent sensing and imaging of pH/copper ions in real samples based on carbon dots-fluorescein isothiocyanate composites. Talanta. 2017 Jan 1;162:65-71
Density 1.5±0.1 g/cm3
Boiling Point 708.6±60.0 °C at 760 mmHg
Melting Point >360 °C(lit.)
Molecular Formula C21H11NO5S
Molecular Weight 389.381
Flash Point 382.4±32.9 °C
Exact Mass 389.035797
PSA 120.44000
LogP 4.00
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.754
Storage condition 2-8°C
Stability Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.
Water Solubility practically insoluble
Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H317-H334
Precautionary Statements P261-P280-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22;R36/37/38;R42/43
Safety Phrases S22-S45-S36/37/39-S26-S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
2321-07-5 structure

2321-07-5

~%

3326-32-7 structure

3326-32-7

Literature: WO2006/84339 A1, ; Page/Page column 30 ;
463-71-8 structure

463-71-8

3326-34-9 structure

3326-34-9

~%

3326-32-7 structure

3326-32-7

Literature: Tomasch, Miriam; Schwed, J. Stephan; Kuczka, Karina; Meyer Dos Santos, Sascha; Harder, Sebastian; Nuesing, Rolf M.; Paulke, Alexander; Stark, Holger ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 9 p. 774 - 779
610-27-5 structure

610-27-5

~%

3326-32-7 structure

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779
108-46-3 structure

108-46-3

~%

3326-32-7 structure

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779
3326-35-0 structure

3326-35-0

~%

3326-32-7 structure

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779
14926-29-5 structure

14926-29-5

~%

3326-32-7 structure

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779
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title: CAS No. 3326-32-7 | Chemsrc address: https://www.chemsrc.com/en/baike/437529.html

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