Name | (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid |
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Synonyms |
D-LeuFmoc-OH
Fmoc-Leu-OH N-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-leucine EINECS 252-662-7 (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpentanoic acid MFCD00037133 Tocris-0675 FMOC-D-LEU Fmoc-D-Leu-OH Fmoc-L-leucine Fmoc-L-Leu-OH L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine Fmoc-D-leucine-OH N-Fmoc-D-leucine D-Fmoc-Leu-OH N-Fmoc-L-leucine D-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- Fmoc-D-Leucine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine |
Description | Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1]. |
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Related Catalog | |
Target |
PPARγ |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 559.8±33.0 °C at 760 mmHg |
Melting Point | 152-156 °C(lit.) |
Molecular Formula | C21H23NO4 |
Molecular Weight | 353.412 |
Flash Point | 292.4±25.4 °C |
Exact Mass | 353.162720 |
PSA | 75.63000 |
LogP | 4.95 |
Vapour Pressure | 0.0±1.6 mmHg at 25°C |
Index of Refraction | 1.583 |
Storage condition | 2~8°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Risk Phrases | R36/37/38 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2924299090 |
Precursor 7 | |
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DownStream 10 | |
HS Code | 2924299090 |
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Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |