Name | Mirtazapine-d3 |
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Description | Mirtazapine D3 (Org3770 D3; 6-Azamianserin D3) is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1]. |
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Related Catalog | |
Target |
5-HT2 Receptor 5-HT3 Receptor |
In Vivo | Mirtazapine (intraperitoneal injection; 10–50 mg/Kg; 14 days) treatment normalizes heart rate, breath rate, anxiety levels and eliminates the hopping behavior observed in MeCP2-null mice, leading to improved phenotypic score[2]. Animal Model: MeCP2 null mice[2] Dosage: 10-50 mg/Kg Administration: Intraperitoneal injection; 10-50 mg/Kg; 14 days Result: Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI. |
References |
Molecular Formula | C17H16D3N3 |
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Molecular Weight | 268.37100 |
Exact Mass | 268.17700 |
PSA | 19.37000 |
LogP | 2.48180 |