BioBioPha
China
Product Name: Pseudoprotodioscin
Price: ￥Inquiry/20mg
Purity: 98.0%
Stocking Period: 1 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pseudoprotodioscin
Price: ￥3200.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pseudoprotodioscin
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

102115-79-7

102115-79-7 structure

102115-79-7 structure

Name: Pseudoprotodioscin
Chemical Name: protogracellin
CAS Number: 102115-79-7
Molecular Formula: C₅₁H₈₂O₂₁
Molecular Weight: 1031.184
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-02-16 08:00:00
Modify Date: 2024-01-02 16:25:18
Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides[1].

Name	protogracellin
Synonyms	PSEUDOPROTOTRIBESTIN β-D-Glucopyranoside, (25R)-3-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranosyl]oxy]furosta-5,20(22)-dien-27-yl (3β,25R)-26-(β-D-Glucopyranosyloxy)furosta-5,20(22)-dien-3-yl 6-deoxy-α-L-mannopyranosyl-(1->;2)-[6-deoxy-α-L-mannopyranosyl-(1->;4)]-β-D-glucopyranoside pseudo-Protodioscin PROTODIOSCIN,PSEUDO β-D-Glucopyranoside, (25R)-26-(β-D-glucopyranosyloxy)furosta-5,20(22)-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[6-deoxy-α-L-mannopyranosyl-(1->4)]- (25R)-26-(β-D-Glucopyranosyloxy)furosta-5,20(22)-dien-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranoside Pseduoprotodioscin (25R)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranosyl]oxy}furosta-5,20(22)-dien-27-yl β-D-glucopyranoside β-D-Glucopyranoside, (3β,25R)-26-(β-D-glucopyranosyloxy)furosta-5,20(22)-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[6-deoxy-α-L-mannopyranosyl-(1->4)]- Pseudoprotodioscin

Description	Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides[1].
Related Catalog	Signaling Pathways >> Epigenetics >> MicroRNA Signaling Pathways >> Metabolic Enzyme/Protease >> Fatty Acid Synthase (FAS) Research Areas >> Metabolic Disease
In Vitro	In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels[1].
References	[1]. Gai Y, et al. Pseudoprotodioscin inhibits SREBPs and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides. Fitoterapia. 2019 Nov;139:104393. [2]. Liang ZZ, et al. Oligofurostanosides from Asparagus cochinchinensis. Planta Med. 1988 Aug;54(4):344-6.

Density	1.45 g/cm3
Molecular Formula	C₅₁H₈₂O₂₁
Molecular Weight	1031.184
Exact Mass	1030.534912
PSA	325.83000
LogP	5.31
Index of Refraction	1.631

Safety Phrases	S24/25
HS Code	29389090