216299-21-7
216299-21-7 structure
- Name: α-Conotoxin AuIB TFA
- Chemical Name: α-Conotoxin AuIB
- CAS Number: 216299-21-7
- Molecular Formula: C65H89N17O21S4
- Molecular Weight: 1572.76000
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
- Create Date: 2017-10-29 15:50:22
- Modify Date: 2025-08-27 13:17:05
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α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC50 of 0.75 μM[1].
| Name | α-Conotoxin AuIB |
|---|---|
| Synonyms |
A-CONOTOXIN AUIB
AuIB globular |
| Description | α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC50 of 0.75 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.75 μM (α3β4 nAChR; in Xenopus oocytes)[1] |
| In Vitro | α-Conotoxin AuIB blocks the α3β4 receptor with >100-fold higher potency than other receptor subunit combinations, including α2β2, α2β4, α3β2, α4β2, α4β4, and α1β1γδ[1]. |
| References |
| Molecular Formula | C65H89N17O21S4 |
|---|---|
| Molecular Weight | 1572.76000 |
| Exact Mass | 1571.53000 |
| PSA | 692.42000 |
| Hazard Codes | T+ |
|---|