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475-38-7

475-38-7 structure
475-38-7 structure
  • Name: Naphthazarin
  • Chemical Name: naphthazarin
  • CAS Number: 475-38-7
  • Molecular Formula: C10H6O4
  • Molecular Weight: 190.15200
  • Catalog: Chemical reagent Organic reagent Bicyclic compound
  • Create Date: 2018-08-27 11:32:51
  • Modify Date: 2025-08-27 21:43:37
  • Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2].
Name naphthazarin
Synonyms 5,8-Dihydroxy-1,4-naphthalenedione
EINECS 207-495-4
MFCD00001685
5,8-Dihydroxy-1,4-naphthoquinone
5,8-dihydroxynaphthalene-1,4-dione
Naphthazarin
Description Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2].
Related Catalog
References

[1]. Seon Young Choi, et al. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. J Neurosci Res. 2012 Sep;90(9):1842-9.

[2]. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74.
Density 1.592g/cm3
Boiling Point 498.2ºC at 760mmHg
Melting Point 220-230 °C(lit.)
Molecular Formula C10H6O4
Molecular Weight 190.15200
Flash Point 269.2ºC
Exact Mass 190.02700
PSA 74.60000
LogP 1.03300
Vapour Pressure 1.51E-10mmHg at 25°C
Index of Refraction 1.71

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL7970000
CHEMICAL NAME :
1,4-Naphthoquinone, 5,8-dihydroxy-
CAS REGISTRY NUMBER :
475-38-7
LAST UPDATED :
199410
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H6-O4
MOLECULAR WEIGHT :
190.16
WISWESSER LINE NOTATION :
L66 BV EVJ GQ JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 124,25,1983
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QL7970000
HS Code 2914690090
HS Code 2914690090
Summary 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
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title: CAS No. 475-38-7 | Chemsrc address: https://www.chemsrc.com/en/baike/244667.html

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