Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Z-Leu-OH
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

GL Biochem (Shanghai) Ltd.
China
Product Name: Z-Leu-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Z-Leu-OH
Price: ￥68.0/5g ￥158.0/25g
Purity: 96.0%
Stocking Period: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Nanjing Peptide Biotech Ltd
China
Product Name: Z-Leu-OH
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-Cbz-L-Leucine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

2018-66-8

2018-66-8 structure

2018-66-8 structure

Name: Z-Leu-OH
Chemical Name: N-benzyloxycarbonyl-L-leucine
CAS Number: 2018-66-8
Molecular Formula: C₁₄H₁₉NO₄
Molecular Weight: 265.305
Catalog: Biochemical Amino acids and their derivatives Leucine derivative
Create Date: 2018-03-21 08:00:00
Modify Date: 2024-01-02 10:54:48
N-[(Phenylmethoxy)carbonyl]-L-leucine is a leucine derivative[1].

Name	N-benzyloxycarbonyl-L-leucine
Synonyms	N-[(Benzyloxy)carbonyl]-L-leucine N-(Benzyloxycarbonyl)-L-leucine (N-(Benzyloxycarbonyl)leucine Z-L-Leucine EINECS 217-960-3 N-Carbobenzyloxy-L-leucine (2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid N-Benzyloxycarbonyl-L-leucine Cbz-L-Leu-OH Carbobenzoxyleucine Benzyloxycarbonylleucine dl-Leucine, N-[(phenylmethoxy)carbonyl]- N-(Benzyloxycarbonyl)-L-leucine N-(B (S)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acid Z-Leu-OH N-Benzyloxycarbonylleucine L-Leucine, N-[(phenylmethoxy)carbonyl]- N-Cbz-L-leucine N-[(Benzyloxy)carbonyl]leucine MFCD00026494 Cbz-L-leucine Leucine, N-[(phenylmethoxy)carbonyl]- Benzyloxycarbonyl-L-leucine N-Carbobenzoxy-L-leucine

Description	N-[(Phenylmethoxy)carbonyl]-L-leucine is a leucine derivative[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Density	1.2±0.1 g/cm3
Boiling Point	442.8±38.0 °C at 760 mmHg
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.305
Flash Point	221.6±26.8 °C
Exact Mass	265.131409
PSA	75.63000
LogP	3.12
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.528
Storage condition	2~8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OH2921000

CHEMICAL NAME :: Leucine, N-carboxy-, N-benzyl ester, L-

CAS REGISTRY NUMBER :: 2018-66-8

BEILSTEIN REFERENCE NO. :: 1253861

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H19-N-O4

MOLECULAR WEIGHT :: 265.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravaginal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 280 mg/kg

SEX/DURATION :: female 28 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979

Symbol	GHS02, GHS08
Signal Word	Warning
Hazard Statements	H226-H351-H361d
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R10;R20/22;R37/38;R40;R41
Safety Phrases	S16-S26-S36/37/39-S45
RIDADR	UN 1993 3/PG 3
WGK Germany	3
RTECS	OH2921000
HS Code	2924299090

Precursor 9
61-90-5 501-53-1 3242-70-4 51021-87-5
64187-30-0 1738-87-0 7517-19-3 53363-87-4
42116-21-2
DownStream 10
33099-08-0 3397-35-1 3589-42-2 14485-80-4
21691-53-2 18830-16-5 20998-86-1 61-90-5
100-39-0 28529-34-2

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%