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2770269-44-6

2770269-44-6 structure

2770269-44-6 structure

Name: LRRK2-IN-8
Chemical Name: LRRK2-IN-8
CAS Number: 2770269-44-6
Molecular Formula: C₁₆H₁₂F₂N₆
Molecular Weight: 326.30
Catalog: Signaling Pathways Autophagy LRRK2
Create Date: 2023-04-03 10:38:10
Modify Date: 2025-08-30 08:38:44
LRRK2-IN-8 is a LRRK2 inhibitor. LRRK2-IN-8 inhibits LRRK2 (wt) and LRRK2 (G2019) with IC50s lower than 10 nM, and inhibits TYK2 and NUAK1 with IC50s of 10-100 nM[1].

Name	LRRK2-IN-8

Description	LRRK2-IN-8 is a LRRK2 inhibitor. LRRK2-IN-8 inhibits LRRK2 (wt) and LRRK2 (G2019) with IC50s lower than 10 nM, and inhibits TYK2 and NUAK1 with IC50s of 10-100 nM[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> Autophagy >> LRRK2 Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Neurological Disease
Target	Tyk2:10-100 nM (IC50) NUAK1:10-100 nM (IC50)
References	[1]. Jean TASSEL, et al. Kinase modulators and methods of use thereof. Patent. WO2022104206.

Molecular Formula	C₁₆H₁₂F₂N₆
Molecular Weight	326.30

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