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2767258-88-6

2767258-88-6 structure

2767258-88-6 structure

Name: METTL3-IN-2
Chemical Name: METTL3-IN-2
CAS Number: 2767258-88-6
Molecular Formula: C₂₅H₂₆N₈O
Molecular Weight: 454.53
Catalog: Research Areas Cancer
Create Date: 2023-01-17 18:48:50
Modify Date: 2025-08-26 19:19:26
METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].

Name	METTL3-IN-2

Description	METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	METTL3-IN-2 inhibits METTL3 activity with an IC50 value of 6.1 nM[1]. METTL3-IN-2 (0-30 μM; 120 h) inhibits cell proliferation of Caov3 cells[1]. METTL3-IN-2 (0-30 μM; 120 h) inhibits growth of KASUMI cells with an IC50 value of 315.8 nM[1]. Cell Proliferation Assay[1] Cell Line: Caov3 cell line Concentration: 0-30 μM Incubation Time: 120 hours Result: Inhibited cell proliferation of Caov3 cells with an IC50 value of 102.5 nM.
References	[1]. Hardick, DJ, et al. Preparation of heteroaromatic compounds as METTL3 inhibitory compounds. WO2022074379. 2022.

Molecular Formula	C₂₅H₂₆N₈O
Molecular Weight	454.53

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