902456-47-7

902456-47-7 structure

Name	Sirt2-IN-5

Description	Sirt2-IN-5 is a potent SIRT2 inhibtor[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Research Areas >> Neurological Disease
Target	SIRT2
In Vitro	Sirt2-IN-5 shows 47.95% SIRT2 inhibition at 100 µM[1].
References	[1]. Sukuroglu, M.K., et al. The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking. Med Chem Res 30, 1915–1924 (2021).

Molecular Formula	C₂₆H₂₇Cl₂N₅O₃
Molecular Weight	528.43