2243151-81-5

2243151-81-5 structure

2243151-81-5 structure

Name: Sirt2-IN-6
Chemical Name: Sirt2-IN-6
CAS Number: 2243151-81-5
Molecular Formula: C₂₆H₂₆N₆O₃S
Molecular Weight: 502.59
Catalog: Signaling Pathways Cell Cycle/DNA Damage Sirtuin
Create Date: 2022-05-21 19:00:49
Modify Date: 2024-01-10 18:48:10
Sirt2-IN-6 (compound 24a) potent and selective inhibitor of SIRT2, with an IC50 of 0.815 μM. Sirt2-IN-6 can be used for the research of cancer[1].

Name	Sirt2-IN-6

Description	Sirt2-IN-6 (compound 24a) potent and selective inhibitor of SIRT2, with an IC50 of 0.815 μM. Sirt2-IN-6 can be used for the research of cancer[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
Target	SIRT2:0.815 μM (IC50)
References	[1]. Yang LL, et, al. X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells. Eur J Med Chem. 2018 Jul 15;155:806-823.

Molecular Formula	C₂₆H₂₆N₆O₃S
Molecular Weight	502.59