2490589-08-5

2490589-08-5 structure

Name: sEH/AChE-IN-1
Chemical Name: sEH/AChE-IN-1
CAS Number: 2490589-08-5
Molecular Formula: C₂₉H₃₁ClF₃N₅O₃
Molecular Weight: 590.04
Create Date: 2022-05-19 18:17:42
Modify Date: 2025-09-09 08:17:48
sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD)[1].

Name	sEH/AChE-IN-1

Description	sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Codony S, et al. Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem. 2022;65(6):4909-4925.

Molecular Formula	C₂₉H₃₁ClF₃N₅O₃
Molecular Weight	590.04