2415085-45-7
2415085-45-7 structure
- Name: PDE4-IN-8
- Chemical Name: PDE4-IN-8
- CAS Number: 2415085-45-7
- Molecular Formula: C18H22BNO4
- Molecular Weight: 327.18
- Create Date: 2022-07-01 17:28:17
- Modify Date: 2025-08-26 20:21:23
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PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1].
| Name | PDE4-IN-8 |
|---|
| Description | PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1]. |
|---|---|
| Related Catalog | |
| Target |
PDE4B2:0.93 nM (IC50) IL4:36.33 nM (IC50) IL-13:4.04 nM (IC50) |
| References |
[1]. Joseph Walter Strohbach, et al. Inhibiteurs de pde4 contenant du bore. WO2020070651A1. |
| Molecular Formula | C18H22BNO4 |
|---|---|
| Molecular Weight | 327.18 |