2760326-29-0
2760326-29-0 structure
- Name: c-Met-IN-9
- Chemical Name: c-Met-IN-9
- CAS Number: 2760326-29-0
- Molecular Formula: C25H19F2N5O3
- Molecular Weight: 475.45
- Create Date: 2022-05-20 20:20:56
- Modify Date: 2024-04-06 18:58:29
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c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1].
| Name | c-Met-IN-9 |
|---|
| Description | c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1]. |
|---|---|
| Related Catalog | |
| Target |
c-Met:12 nM (IC50) |
| In Vitro | c-Met-IN-9 (Compound T14) shows remarkable antiproliferative activities against MKN-45, A549 and H460 cell lines with IC50 values of 0.64 μM, 1.92 μM and 2.68 μM, respectively[1]. c-Met-IN-9 could inhibit cells colony formation, induce cells apoptosis, and inhibit cells motility[1]. |
| References |
| Molecular Formula | C25H19F2N5O3 |
|---|---|
| Molecular Weight | 475.45 |