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27262-48-2

27262-48-2 structure
27262-48-2 structure

Name levobupivacaine hydrochloride (anhydrous)
Synonyms levobupivacaine monohydrochloride
Levobupivacainehydrochloride
(S)-(-)-BUPIVACAINE HCL
Levobupivacaine Hydrochloride
L-BUPIVACAINE HYDROCHLORIDE
L-(-)-Bupivacaine
(S)-Bupivacaine hydrochloride
(RS)-bupivacaine hydrochloride
BUPIVACAINE HCL
Levobupivacaine HCl
bupivacaine.hydrochloride
MFCD01704265
(-)-Bupivacaine hydrochloride
Chirocaine
(2S)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride (1:1)
2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, (2S)-, hydrochloride (1:1)
1-butyl-piperidine-2-carboxylic acid-(2,6-dimethyl-anilide),hydrochloride
LEVAMISOLHCLSALT
(2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride (1:1)
(S)-(-)-Bupivacaine hydrochloride
(S)-Bupivacaine
(-)-Bupicaine Hydrochloride
bupicainehydrochloride(-)
Levobupivacaine (hydrochloride)
Boiling Point 423.4ºC at 760 mmHg
Melting Point 254 °C (dec.)(lit.)
Molecular Formula C18H29ClN2O
Molecular Weight 324.889
Flash Point 209.9ºC
Exact Mass 324.196838
PSA 23.55000
LogP 4.74080
Vapour Pressure 2.24E-07mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK6120000
CHEMICAL NAME :
2',6'-Pipecoloxylidide, 1-butyl-, hydrochloride, (-)-
CAS REGISTRY NUMBER :
27262-48-2
LAST UPDATED :
198209
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H28-N2-O.Cl-H
MOLECULAR WEIGHT :
324.94
WISWESSER LINE NOTATION :
T6NTJ A4 BVMR B1 F1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
63 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
207 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes T+: Very toxic;Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases S22-S36/37/39-S45-S36/37-S53
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS TK6125000
HS Code 2942000000
HS Code 2942000000