Name | 3-Hydroxytyramine hydrochloride |
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Synonyms |
3,4-Dihydroxy-b-phenethylamine Hydrochloride
4-(2-aminoéthyl)benzène-1,2-diol chlorhydrate b-(3,4-Dihydroxyphenyl)ethylamine Hydrochloride Tensamin 4-(2-Aminoethyl)benzene-1,2-diol hydrochloride (1:1) Rascordin Pyrocatechol, 4- (2-aminoethyl)-, hydrochloride 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride (1:1) 4-(2-aminoethyl)benzene-1,2-diol,hydrochloride 1,2-Benzenediol, 4- (2-aminoethyl)-, hydrochloride 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride (1:1) 4-(2-aminoethyl)-Pyrocatechol hydrochloride 4-(2-Aminoethyl)benzol-1,2-diolhydrochlorid EINECS 200-527-8 MFCD00012898 4-(2-Aminoethyl)catechol, hydrochloride β-(3,4-Dihydroxyphenyl)ethylamine hydrochloride Dopamine (hydrochloride) |
Description | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.Target: Dopamine ReceptorDopamine (or 3,4-dihydroxyphenethylamine) is a neuroendocrine transmitter in the catecholamine and phenethylamine families that plays a number of important roles in the brain and bodies of humans. Several important diseases of the nervous system are associated with dysfunctions of the dopamine system. Outside the nervous system, dopamine functions in several parts of the body as a local chemical messenger. In the blood vessels, it inhibits norepinephrine release and acts as a vasodilator; in the kidneys, it increases sodium excretion and urine output; in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. A variety of important drugs work by altering the way the body makes or uses dopamine. Dopamine itself is available for intravenous injection: although it cannot reach the brain from the bloodstream, its peripheral effects make it useful in the treatment of heart failure or shock, especially in newborn babies. L-DOPA, the metabolic precursor of dopamine, does reach the brain and is the most widely used treatment for Parkinson's disease. From Wikipedia. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
References |
Boiling Point | 337.7ºC at 760 mmHg |
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Melting Point | 248-250 °C(lit.) |
Molecular Formula | C8H12ClNO2 |
Molecular Weight | 189.639 |
Exact Mass | 189.055649 |
PSA | 66.48000 |
LogP | 2.10130 |
Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
Water Solubility | soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
Symbol |
GHS07, GHS09 |
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Signal Word | Warning |
Hazard Statements | H302-H410 |
Precautionary Statements | P273-P501 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi:Irritant |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | UN 3077 9/PG 3 |
WGK Germany | 2 |
RTECS | UX1092000 |
HS Code | 29222900 |
Flash Point(F) | 51.8 °F |
Flash Point(C) | 11 °C |
~96% 62-31-7 |
Literature: Kohno; Sasao; Murahashi Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1252 - 1254 |
~76% 62-31-7 |
Literature: Velcicky, Juraj; Soicke, Arne; Steiner, Roland; Schmalz, Hans-Guenther Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6948 - 6951 |
~99% 62-31-7 |
Literature: Bernini, Roberta; Crisante, Fernanda; Barontini, Maurizio; Fabrizi, Giancarlo Synthesis, 2009 , # 22 art. no. P09409SS, p. 3838 - 3842 |
~% 62-31-7 |
Literature: Journal of the American Chemical Society, , vol. 133, # 18 p. 6948 - 6951 |
Precursor 4 | |
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DownStream 10 | |
HS Code | 29222900 |
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