1562-85-2

1562-85-2 structure

Name: Gallocyanine
Chemical Name: Gallocyanine
CAS Number: 1562-85-2
Molecular Formula: C₁₅H₁₃ClN₂O₅
Molecular Weight: 336.727
Catalog: Biochemical Biochemical reagent Biological dye
Create Date: 2018-09-07 07:24:34
Modify Date: 2024-01-03 19:11:43
Gallocyanine chloride, a synthetic blue dyestuff, blocks DKK1 inhibitory activity by disrupting DKK1/LRP6 interaction. Its association with LRP6 is weak (IC50 of about 3 μM in the inhibition of DKK1 binding). Gallocyanine dye acts as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies[1].

Name	Gallocyanine
Synonyms	EINECS 216-345-7 C.I. Mordant Blue 10 (8CI) MFCD00011926 1-Carboxy-7-(dimethylamino)-3,4-dihydroxyphenoxazin-5-ium chloride 7-Dimethylamino-4-hydroxy-3-oxo-phenoxazine-1-carboxylic acid Phenoxazinium, 1-carboxy-7-(dimethylamino)-3,4-dihydroxy-, chloride (1:1) Gallocyanine Phenoxazin-5-ium, 1-carboxy-7- (dimethylamino)-3,4-dihydroxy-, chloride

Description	Gallocyanine chloride, a synthetic blue dyestuff, blocks DKK1 inhibitory activity by disrupting DKK1/LRP6 interaction. Its association with LRP6 is weak (IC50 of about 3 μM in the inhibition of DKK1 binding). Gallocyanine dye acts as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> Wnt Research Areas >> Neurological Disease
References	[1]. Spyros Mpousis, et al. Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies. Eur J Med Chem. 2016 Jan 27;108:28-38.

CHEMICAL NAME :: Phenoxazin-5-ium, 1-carboxy-7-(dimethylamino)-3,4-dihydroxy-, chloride

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMNTA4 American Naturalist. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1867- Volume(issue)/page/year: 87,295,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3052 No. of Facilities: 22 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 131 (estimated) No. of Female Employees: 81 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SP7692000
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%