2414572-47-5
2414572-47-5 structure
- Name: BDTX-189
- Chemical Name: BDTX-189
- CAS Number: 2414572-47-5
- Molecular Formula: C29H29ClN6O4
- Molecular Weight: 561.03
- Create Date: 2021-01-14 18:15:04
- Modify Date: 2024-01-03 10:55:00
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BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, includes EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity.
| Name | BDTX-189 |
|---|
| Description | BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, includes EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity. |
|---|
| Molecular Formula | C29H29ClN6O4 |
|---|---|
| Molecular Weight | 561.03 |
| Storage condition | -20°C |