2253744-58-8

2253744-58-8 structure

Name: DMNPE-4 AM-caged-calcium
Chemical Name: DMNPE-4 AM-caged-calcium
CAS Number: 2253744-58-8
Molecular Formula: C₃₄H₄₇N₃O₂₂
Molecular Weight: 849.74
Catalog: Research Areas Neurological Disease
Create Date: 2021-01-09 22:20:07
Modify Date: 2025-08-25 18:17:19
DMNPE-4 AM-caged-calcium, photolabile analogues of EGTA, is an extremely effective Ca2+ selective cage, with a Kd for Ca2+ of 48 nM and 19 nM at pH 7.2 and pH 7.4, respectively. DMNPE-4 AM-caged-calcium has a lower affinity for Ca2+ (Kd=~2 nM) after photolysis[1][2].

Name	DMNPE-4 AM-caged-calcium

Description	DMNPE-4 AM-caged-calcium, photolabile analogues of EGTA, is an extremely effective Ca2+ selective cage, with a Kd for Ca2+ of 48 nM and 19 nM at pH 7.2 and pH 7.4, respectively. DMNPE-4 AM-caged-calcium has a lower affinity for Ca2+ (Kd=~2 nM) after photolysis[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Ellis-Davies GCR, et, al. Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium. 2006 Jan;39(1):75-83. [2]. DelPrincipe F, et, al. Two-photon and UV-laser flash photolysis of the Ca2+ cage, dimethoxynitrophenyl-EGTA-4. Cell Calcium. 1999 Jan;25(1):85-91.

Molecular Formula	C₃₄H₄₇N₃O₂₂
Molecular Weight	849.74