439080-01-0

439080-01-0 structure

Name: O-2093
Chemical Name: (5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)-5,8,11,14-icosatetraenamide
CAS Number: 439080-01-0
Molecular Formula: C₃₄H₄₃Cl₂NO₃
Molecular Weight: 584.62
Create Date: 2018-07-19 23:37:13
Modify Date: 2025-08-25 18:28:03
O-2093 is a selective endocannabinoid anandamide (AEA) reuptake inhibitor with IC50 of 17.3 μM[1].

Name	(5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)-5,8,11,14-icosatetraenamide
Synonyms	5,8,11,14-Eicosatetraenamide, N,N-bis[(3-chloro-4-hydroxyphenyl)methyl]-, (5Z,8Z,11Z,14Z)- (5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)icosa-5,8,11,14-tetraenamide (5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)-5,8,11,14-icosatetraenamide

Description	O-2093 is a selective endocannabinoid anandamide (AEA) reuptake inhibitor with IC50 of 17.3 μM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
In Vivo	O-2093 (1 mg/kg, i.v.) 可显着抑制 CREATE 小鼠的肢体痉挛[1]。
References	[1]. Alessia Ligresti, et al. New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis.