957-75-5

957-75-5 structure

Name: 5-Bromouridine
Chemical Name: 5-bromouridine
CAS Number: 957-75-5
Molecular Formula: C₉H₁₁BrN₂O₆
Molecular Weight: 323.10
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-05-06 08:00:00
Modify Date: 2024-01-02 10:36:12
5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-bromouridine
Synonyms	5-bromo-uridin 5-Br-rU Uridine, 5-bromo- EINECS 213-486-6 5-Bromouracil ribonucleoside bromouridine 5-BrU 5'-BROMOURIDINE 5-Bromouracil-1-β-D-ribofuranoside 5-Bromouridine 5-BROMO-URIDINE(5-BRU) 5-bromo-UMP MFCD00006528 1-β-ribofuranosyl-5-bromo-uracil 5-Bromo-D-uridine

Description	5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 43,205,1980

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 43,205,1980