2149-76-0
2149-76-0 structure
- Name: 5-Aminouridine
- Chemical Name: 5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- CAS Number: 2149-76-0
- Molecular Formula: C9H13N3O6
- Molecular Weight: 259.21600
- Catalog: Signaling Pathways Anti-infection Fungal
- Create Date: 2018-03-02 08:00:00
- Modify Date: 2025-09-12 16:30:47
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5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2][3].
| Name | 5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
|---|---|
| Synonyms |
5-amino-uridine
Uridine,5-amino 5-Aminouridin |
| Description | 5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites[4]. |
| In Vivo | 5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma[1]. |
| References |
[1]. Smith DA, et al. Studies on 5-aminouridine. Biochim Biophys Acta. 1966 May 19;119(2):221-8. |
| Density | 1.712g/cm3 |
|---|---|
| Molecular Formula | C9H13N3O6 |
| Molecular Weight | 259.21600 |
| Exact Mass | 259.08000 |
| PSA | 150.80000 |
| Index of Refraction | 1.666 |
| WGK Germany | 3 |
|---|---|
| HS Code | 2934999090 |
|
~80%
2149-76-0 |
| Literature: Repkova; Ivanova; Komarova; Meshchaninova; Kuznetsova; Venyaminova Russian Journal of Bioorganic Chemistry, 1999 , vol. 25, # 9 p. 612 - 622 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |