Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Imidodicarbonimidicdiamide, N-(3-chlorophenyl)-, hydrochloride (1:1)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2113-05-5

2113-05-5 structure

Name: 1-(3-chlorophenyl)biguanide hydrochloride
Chemical Name: 2-(3-chlorophenyl)-1-(diaminomethylidene)guanidine,hydrochloride
CAS Number: 2113-05-5
Molecular Formula: C₈H₁₁Cl₂N₅
Molecular Weight: 248.11
Catalog: Chemical reagent Organic reagent Barium salt
Create Date: 2018-06-12 08:50:14
Modify Date: 2024-01-10 07:37:37
m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1].

Name	2-(3-chlorophenyl)-1-(diaminomethylidene)guanidine,hydrochloride
Synonyms	1-(3-Chlorophenyl)biguanide hydrochloride m-Chlorophenylbiguanide hydrochloride MFCD00053019 N-m-Chlorophenylbiguanide hydrochloride m-CPBG hydrochloride

Description	m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
In Vivo	m-CPBG hydrochloride (80 and 160 nM) 显著减少急性盐负荷引起的水摄入量[1]。 m-CPBG hydrochloride (third ventricle injection; 160 nM) 显著抑制低血容量动物的水摄入[1]。 m-CPBG hydrochloride (third ventricle injection; 320 nM) 减少缺水大鼠的水摄入量[1]。 m-CPBG hydrochloride (central administration）抑制中枢胆碱能和血管紧张素能通路药理学激活诱导的水摄入[1]。 Animal Model: Wistar male rats[1] Dosage: 80, 160 and 320 nM Administration: Ventricle injection Result: Decreased water intake induced by water deprivation, acute salt load and hypovolemia.
References	[1]. Castro L, et al. Central 5-HT(3) receptors and water intake in rats. Physiol Behav. 2002;77(2-3):349-359.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,521,1967

REFERENCE :: IJOCAP Indian Journal of Chemistry. (New Delhi, India) V.1-13, 1963-75. Divided into Indian Journal of Chemistry, Section A and Indian Journal of Chemistry, Section B. Volume(issue)/page/year: 1,218,1962

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DU1780000

127099-85-8

108-42-9

2113-05-5