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1538-09-6

1538-09-6 structure
1538-09-6 structure
  • Name: Penicillin G benzathine
  • Chemical Name: benzylpenicillin benzathine
  • CAS Number: 1538-09-6
  • Molecular Formula: C48H56N6O8S2
  • Molecular Weight: 909.124
  • Catalog: API Antibiotics Penicillin
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2025-08-20 23:15:47
  • Penicillin G benzathine (Benzathine benzylpenicillin) is an antibiotic against many bacterial infections[1].

Name benzylpenicillin benzathine
Synonyms leomypen
neolin
dibencil
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-, (2S,5R,6R)-, compd. with N,N-bis(phenylmethyl)-1,2-ethanediamine (2:1)
benzathine benzylpenicillin
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine (2:1)
benzapen
moldamin
N,N'-Dibenzylethylenedi amine bis[benzylpenicillin]
Megacillin
pendepon
DBED-penicillin
Penicillin G N,N'-dibenzylethylenediamine salt
[2S-(2a,5a,6b)]-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compd with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1)
cillenta
N,N'-Dibenzyl-1,2-ethanediaminium bis{(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate}
penadur
Benzathine Penicillin G
bicillin
longicil
Boiling Point 663.3ºCat 760 mmHg
Melting Point 123-124ºC
Molecular Formula C48H56N6O8S2
Molecular Weight 909.124
Flash Point 355ºC
Exact Mass 908.360107
PSA 248.08000
LogP 5.72700
Vapour Pressure 1.69E-18mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XH9425000
CAS REGISTRY NUMBER :
1538-09-6
LAST UPDATED :
199707
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C32-H36-N4-O8-S2.C16-H20-N2
MOLECULAR WEIGHT :
909.22
WISWESSER LINE NOTATION :
T45 ANV ESTJ CMV1R& F F GVQ & 2 &622

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,774,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
460 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 4,633,1954 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
22905 ug/kg
SEX/DURATION :
female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 82,1076,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1268 No. of Facilities: 49 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1896 (estimated) No. of Female Employees: 921 (estimated)
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H302-H334
Precautionary Statements P261-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 36
RIDADR NONH for all modes of transport
RTECS XH9425000
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