Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Penicillin G potassium
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Penicillin G potassium
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Penicillin G potassium
Price: $Inquiry/25mg $Inquiry/50mg $Inquiry/250mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Potassium benzylpenicillin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

113-98-4

113-98-4 structure

Name: Penicillin G potassium
Chemical Name: benzylpenicillin potassium
CAS Number: 113-98-4
Molecular Formula: C₁₆H₁₇KN₂O₄S
Molecular Weight: 372.480
Catalog: Pharmaceutical intermediate OLED material intermediate
Create Date: 2018-07-14 18:16:03
Modify Date: 2024-01-02 19:50:07
Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas.

Name	benzylpenicillin potassium
Synonyms	Benzyl Penicillinate Potassium Salt MFCD00036193 Benzylpenicillinic acid potassium salt Forpen Potassium (1E)-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylethanimidate Benzylpenicillin potassium Potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Tabilin Hipercilina Hyasorb Penicillin G potassium Benzylpenicillin Potassium Salt Monopen Eskacillin 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(1E)-1-hydroxy-2-phenylethylidene]amino]-3,3-dimethyl-7-oxo-, potassium salt, (2S,5R,6R)- (1:1) [2S-(2a,5a,6b)]-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monopotassium Salt POTASSIUM PENICILLIN G Hylenta Notaral 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, monopotassium salt, (2S,5R,6R)- Pentid Potassium benzylpenicillinate potassium,(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate EINECS 204-038-0 Scotcil Penicillin G potassium salt 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-, potassium salt, (2S,5R,6R)- (1:1) Penicillin G (potassium)

Description	Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
References	[1]. Roussel AJ, et al. Evaluation of the effects of penicillin G potassium and potassium chloride on the motility of the large intestine in horses. Am J Vet Res. 2003 Nov;64(11):1360-3. [2]. Byra C, et al. Decreased mortality of weaned pigs with Streptococcus suis with the use of in-water potassium penicillin G. Can Vet J. 2011 Mar;52(3):272-6.

Melting Point	214-217 â„ƒ
Molecular Formula	C₁₆H₁₇KN₂O₄S
Molecular Weight	372.480
Exact Mass	372.054596
PSA	114.84000
Index of Refraction	294 ° (C=1， H2O)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH9700000

CHEMICAL NAME :: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenylacetamido)-, monopotassium salt

CAS REGISTRY NUMBER :: 113-98-4

LAST UPDATED :: 199707

DATA ITEMS CITED :: 21

MOLECULAR FORMULA :: C16-H17-N2-O4-S.K

MOLECULAR WEIGHT :: 372.51

WISWESSER LINE NOTATION :: T45 ANV ESTJ CMV1R& F1 F1 GVQ &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11250 mg/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 243 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6257 mg/kg

TOXIC EFFECTS :: Behavioral - excitement

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5848 mg/kg

TOXIC EFFECTS :: Behavioral - hallucinations, distorted perceptions Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 382 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - ulceration or bleeding from stomach

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 374 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 303 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1180 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 312 mg/kg/14W-I

TOXIC EFFECTS :: Gastrointestinal - changes in pancreatic weight Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - death

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 200 mg/kg/8D

REFERENCE :: JOURAA Journal of Urology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1917- Volume(issue)/page/year: 112,348,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81952 No. of Facilities: 1261 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3510 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81952 No. of Facilities: 504 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 27005 (estimated) No. of Female Employees: 20458 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn
Risk Phrases	42/43-34-11
Safety Phrases	36/37-45-36/37/39-26-16
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	XH9700000
HS Code	2941109900

61-33-6

~96%

113-98-4

Literature: WO2007/63107 A1, ; Page/Page column 7-8 ;

80127-23-7

~94%

58105-49-0

113-98-4

Literature: Journal of Organic Chemistry, , vol. 47, # 3 p. 587 - 590

80127-23-7

~93%

113-98-4

Literature: Journal of Organic Chemistry, , vol. 47, # 3 p. 587 - 590

Precursor 1
61-33-6
DownStream 7
52-66-4 551-16-6 54-35-3 52-67-5
124827-15-2 51-17-2 621-72-7

HS Code	2941109900

113-98-4	53956-74-4
51164-31-9	61-33-6
41372-02-5	1538-09-6
653-89-4	69-57-8
6130-64-9	3344-16-9
1303427-39-5	1092922-32-1
6598-84-1	1092728-64-7
1020743-37-6	1200131-73-2
769123-63-9	1200131-31-2
56194-11-7	1200129-78-7