1416133-88-4
1416133-88-4 structure
- Name: JW 618
- Chemical Name: 1,1,1,3,3,3-hexafluoropropan-2-yl methyl(3-(pyridin-4-yl)benzyl)-carbamate
- CAS Number: 1416133-88-4
- Molecular Formula: C17H14F6N2O2
- Molecular Weight: 392.296
- Create Date: 2017-11-18 16:09:34
- Modify Date: 2025-10-14 05:56:17
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JW 618 is an inhibitor of MAGL that displays IC50 values of 123, 385, and 6.9 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.
| Name | 1,1,1,3,3,3-hexafluoropropan-2-yl methyl(3-(pyridin-4-yl)benzyl)-carbamate |
|---|---|
| Synonyms |
jw 618
1,1,1,3,3,3-Hexafluoro-2-propanyl methyl[3-(4-pyridinyl)benzyl]carbamate Carbamic acid, N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester jw618 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 380.0±42.0 °C at 760 mmHg |
| Molecular Formula | C17H14F6N2O2 |
| Molecular Weight | 392.296 |
| Flash Point | 183.6±27.9 °C |
| Exact Mass | 392.095947 |
| PSA | 42.43000 |
| LogP | 5.70 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.486 |