1628207-16-8

1628207-16-8 structure

Name: CB-618 sodium salt
Chemical Name: Sodium ({[(2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)oxidanide
CAS Number: 1628207-16-8
Molecular Formula: C₈H₁₀N₄O₆S_.Na
Molecular Weight: 312.235
Create Date: 2020-01-11 18:55:03
Modify Date: 2025-09-01 13:28:40
CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.

Name	Sodium ({[(2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)oxidanide
Synonyms	1,6-Diazabicyclo[3.2.1]octan-7-one, 2-(1,3,4-oxadiazol-2-yl)-6-(sulfooxy)-, sodium salt, (2S,5R)- (1:1) Sodium ({[(2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)oxidanide

Description	CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.
References	References 1. VanScoy BD, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3891-6. 2. Ambrose PG, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00630-17. View Related Products by Target Bacterial