1463520-70-8
1463520-70-8 structure
- Name: CB-618
- Chemical Name: (2S,5R)-2-(1,3,4-Oxadiazol-2-yl)-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octan-7-one
- CAS Number: 1463520-70-8
- Molecular Formula: C8H10N4O6S
- Molecular Weight: 290.253
- Create Date: 2020-01-12 11:15:12
- Modify Date: 2025-08-25 12:02:49
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CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.
| Name | (2S,5R)-2-(1,3,4-Oxadiazol-2-yl)-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octan-7-one |
|---|---|
| Synonyms |
1,6-Diazabicyclo[3.2.1]octan-7-one, 2-(1,3,4-oxadiazol-2-yl)-6-(sulfooxy)-, (2S,5R)-
(2S,5R)-2-(1,3,4-Oxadiazol-2-yl)-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octan-7-one |
| Description | CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml. |
|---|---|
| References | References 1. VanScoy BD, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3891-6. 2. Ambrose PG, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00630-17. View Related Products by Target Bacterial |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Molecular Formula | C8H10N4O6S |
| Molecular Weight | 290.253 |
| Exact Mass | 290.032104 |
| LogP | -2.45 |
| Index of Refraction | 1.685 |