313649-08-0
313649-08-0 structure
- Name: UCF-101
- Chemical Name: 5-[[5-[2-(dihydroxyamino)phenyl]furan-2-yl]methylidene]-1,3-diphenyl-2-sulfanylidene-1,3-diazinane-4,6-dione
- CAS Number: 313649-08-0
- Molecular Formula: C27H19N3O5S
- Molecular Weight: 497.522
- Create Date: 2018-06-26 18:13:05
- Modify Date: 2024-01-08 14:59:09
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UCF-101 is a selective inhibitor of the pro-apoptotic mitochondrial serine protease Omi/HtrA2 involved in the cellular response to thermal and oxidative stress.
| Name | 5-[[5-[2-(dihydroxyamino)phenyl]furan-2-yl]methylidene]-1,3-diphenyl-2-sulfanylidene-1,3-diazinane-4,6-dione |
|---|---|
| Synonyms |
5-({5-[2-(Dihydroxyamino)phenyl]-2-furyl}methylene)-1,3-diphenyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
4,6(1H,5H)-Pyrimidinedione, 5-[[5-[2-(dihydroxyamino)phenyl]-2-furanyl]methylene]dihydro-1,3-diphenyl-2-thioxo- |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 708.4±70.0 °C at 760 mmHg |
| Molecular Formula | C27H19N3O5S |
| Molecular Weight | 497.522 |
| Flash Point | 382.3±35.7 °C |
| Exact Mass | 497.104553 |
| PSA | 129.55000 |
| LogP | 5.07 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.800 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |