38146-42-8

38146-42-8 structure

Name: Decamethoxine
Chemical Name: N,N'-Bis{2-[(2-isopropyl-5-methylcyclohexyl)oxy]-2-oxoethyl}-N,N, N',N'-tetramethyl-1,10-decanediaminium dichloride
CAS Number: 38146-42-8
Molecular Formula: C₃₈H₇₄Cl₂N₂O₄
Molecular Weight: 693.91
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-09-23 13:28:35
Modify Date: 2024-01-09 22:41:51
Decamethoxine (Septefril) is a cationic gemini surfactant. Decamethoxine exhibits strong bactericidal and fungicidal effects. Decamethoxine modifies the permeability of the microbial cell membrane, resulting in the destruction and death of diverse microorganisms[1][2].

Name	N,N'-Bis{2-[(2-isopropyl-5-methylcyclohexyl)oxy]-2-oxoethyl}-N,N, N',N'-tetramethyl-1,10-decanediaminium dichloride
Synonyms	MFCD02654058

Description	Decamethoxine (Septefril) is a cationic gemini surfactant. Decamethoxine exhibits strong bactericidal and fungicidal effects. Decamethoxine modifies the permeability of the microbial cell membrane, resulting in the destruction and death of diverse microorganisms[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Decamethoxine (Septefril) has a wide spectrum of antimicrobial action on Gram-positive bacteria (Staphylococcus, Streptococcus, Pneumococcus), Gram-negative bacteria (Pseudomonoas, Neisseria gonorrhoeae, Chlamydia trachomatis), protozoa, dermatophyte, yeast-like fungi of Candida genus, and viruses[1]. Decamethoxine at a concentration of 10 µg/ml drastically reduces the adhesion of coryneform bacteria, Salmonella, Staphylococcus, and Escherichia [2].
References	[1]. Kovalchuk V, et al. Naturally Drug-Loaded Chitin: Isolation and Applications. Mar Drugs. 2019;17(10):574. Published 2019 Oct 10. [2]. Nazarchuk OA, et al. The research of antimicrobial efficacy of antiseptics decamethoxin, miramistin and their effect on nuclear DNA fragmentation and epithelial cell cycle. Wiad Lek. 2019;72(3):374-380.

Hazard Codes	Xi