Antiproliferative agent-5

Names

[ Name ]:
Antiproliferative agent-5

Biological Activity

[Description]:

Antiproliferative against-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative against-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative against-5 can be used for researching anticancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

Signaling Pathways >> Autophagy >> Autophagy

[Target]

ROS, Autophagy[1]

[References]

[1]. Wang S, et al. Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway. Eur J Med Chem. 2020;203:112630.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₂₁BrN₈OS

[ Molecular Weight ]:
597.49

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.