Antiproliferative agent-13

Names

[ Name ]:
Antiproliferative agent-13

Biological Activity

[Description]:

Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

IC50: 32.7 nM (A375 cells)[1]

[In Vitro]

Antiproliferative agent-13 (0-10 μM; 72 h) affects proliferation of human A375 melanoma cells[1]. Cell Proliferation Assay[1] Cell Line: A375 melanoma cell line Concentration: 0-10000 nM Incubation Time: 72 hours Result: Showed an anti-proliferative activity to human A375 melanoma cells with an IC50 value of 32.7 nM.

[References]

[1]. Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₈N₂O₆

[ Molecular Weight ]:
382.37

Antiproliferative agent-13

Names

Biological Activity

Chemical & Physical Properties

Related Compounds